Cowell Computer Consulting

If inDesign is crashing when you quit it, launch it, when you activate fonts or at any other time, you should consider removing or replacing the following file:

$HOME/Library/Preferences/Adobe\ InDesign/Version\ 5.0/InDesign\ Defaults

It appears to contain font information among other things. You care about this because if you were to have activated a corrupt font, or a font with a duplicate postscript name, your problems may continue even after you resolve the font issue because that font will still be cached in here.

eg.

...
@Semibold
@MyriadPro-Semibold
@Myriad Pro Semibold
@Semibold
@Myriad Pro Semibold
8@Version 2.007;PS 002.000;Core 1.0.38;makeotf.lib1.7.9032
@Semibold Italic
@MyriadPro-SemiboldIt
@Myriad Pro Semibold Italic
@Semibold Italic
...